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Coupling & Cross-Linking Reagents, Linkers, Ligand

Leading Wholesaler of hatu (cas number: 148893-10-1), hbtu (cas number: 94790-37-1), hoat (cas number: 39968-33-7), hobt hydrate (cas number: 123333-53-9) and hobt anyhrous (cas number: 2592-95-2) from Mumbai.
HATU (CAS Number: 148893-10-1)

HATU (CAS Number: 148893-10-1)

Rs 1,000  / KgGet Best Price

Minimum Order Quantity: 1 Kg

Packaging Size1 kg / 5 kg / 10 kg / 25 kg
Packaging TypeBottle / Drum
ColorWhite to Off White
Physical StatePowder
Purity>98%
Molecular Weight380.23
Empirical Formula (Hill Notation)C10H15F6N6OP
CAS Number148893-10-1

Synonym: 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate, N-[(Dimethylamino)-1H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide


Application : 

Reagent for:
Synthesis of Aurora A kinase inhibitors
HPLC assay to determine D- and L- acid enantiomers in human plasma
Amide bond formation reactions

Catalyst for:
Selective acylation
Selecocyclization-oxidation deselenation sequence

Peptide coupling reagent.

Preparation of N-arylsulfonamide-linked peptides by solid-phase synthesis.

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HBTU (CAS Number: 94790-37-1)

HBTU (CAS Number: 94790-37-1)

Rs 1,000  / KgGet Best Price

Minimum Order Quantity: 1 Kg

Packaging Size1 kg / 5 kg / 10 kg / 25 kg
Physical StatePowder
ColorWhite
Packaging TypeBottle / Drum
Purity>98%
Molecular Weight379.24
CAS Number94790-37-1
Empirical Formula (Hill Notation)C11H16F6N5OP

Synonym: N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate, O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate


Application :

HBTU is a peptide coupling agent for peptide synthesis. It has also been used in standard Fmoc-based solid-phase peptide synthesis (SPPS) protocol.

Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields.

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HOAT (CAS Number: 39968-33-7)

HOAT (CAS Number: 39968-33-7)

Rs 1,000  / GramGet Best Price

Minimum Order Quantity: 500 Gram

Packaging Size500 gm / 1 kg / 5 kg / 10 kg
Packaging TypeBottle
ColorWhite to Off White
Physical StatePowder
Purity>98%
Molecular Weight136.11
CAS Number39968-33-7
Empirical Formula (Hill Notation)C5H4N4O

Synonym: 1-Hydroxy-7-azabenzotriazole, HOAt


1-Hydroxy-7-azabenzotriazole (HOAt) is a triazole used as a peptide coupling reagent. It suppresses the loss of chirality.

HOAt has a melting point between 213 and 216 degrees Celsius.  As a liquid, it is transparent and without any color.

Other Notes : 

Coupling additive for efficient racemization-free coupling in peptide synthesis; segment coupling.

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HOBT Hydrate (CAS Number: 123333-53-9)

HOBT Hydrate (CAS Number: 123333-53-9)

Rs 1,000  / KgGet Best Price

Minimum Order Quantity: 1 Kg

Physical StatePowder
Packaging Size1 kg / 5 kg / 10 kg / 25 kg
Packaging TypeBottle / Drum
Purity>99%
Molecular Weight135.12 (anhydrous basis)
CAS Number123333-53-9
Empirical Formula (Hill Notation)C6H5N3O . xH2O
Synonym: N-Hydroxybenzotriazole Monohydrate, HOBt Hydrate    

Hydroxybenzotriazole (abbreviated HOBt) is an organic compound that is a derivative of benzotriazole. It is a white crystalline powder, which as a commercial product contains some water (~11.7% wt as the HOBt monohydrate crystal). Anhydrous HOBt is explosive.

It is mainly used to suppress the racemization of single-enantiomer chiral molecules and to improve the efficiency of peptide synthesis.


Other Notes : 

Widely used additive to decrease racemization in the carbodiimide peptide coupling; Racemization-free condensation of peptide fragments

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HOBT Anyhrous (CAS Number: 2592-95-2)

HOBT Anyhrous (CAS Number: 2592-95-2)

Rs 1,000  / KgGet Best Price

Minimum Order Quantity: 1 Kg

Packaging Size1 kg / 5 kg / 10 kg / 25 kg
Physical StatePowder
ColorWhite to Off White
Packaging TypeBottle / Drum
Purity>99%
Molecular Weight135.13
CAS Number2592-95-2
Empirical Formula (Hill Notation)C6H5N3O

Synonym: N-Hydroxybenzotriazole

Hydroxybenzotriazole (abbreviated HOBt) is an organic compound that is a derivative of benzotriazole. It is a white crystalline powder, which as a commercial product contains some water (~11.7% wt as the HOBt monohydrate crystal). Anhydrous HOBt is explosive.

It is mainly used to suppress the racemization of single-enantiomer chiral molecules and to improve the efficiency of peptide synthesis.


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